Jenks Health Team - Family Medicine
Combining New Technologies with the Expertise
and Safety of Traditional Medicine
Jenks Health Team, 715 West Main Street, Suite K, Jenks, Oklahoma 74037
Hyperbaric Department: 918-299-2658, HBOT Fax 918-299-2693
Email: firstname.lastname@example.org, www.jenkshealthteam.com
Hyperbaric Oxygen Therapy
What is Hyperbaric Oxygen Therapy?
Hyperbaric oxygen therapy (HBOT) is a medical treatment in which the patient breathes 100% oxygen
while inside a pressurized chamber.
How does HBOT Work?
Oxygen, under pressure, dissolves into the fluid portion of the body, elevating arterial oxygen levels up
to 20 times higher than normal. The oxygen rich liquid portion of the blood can deliver therapeutic levels
of oxygen to areas of poor circulation.
Increased Tissue Oxygen
Oxygen is essential for the proper functioning of every cell in the body. Greatly increased oxygen levels
from HBOT allow increased cellular metabolism, improved waste removal, and a dramatically accelerated
rate of healing.
What Effect Could HBOT Have?
Temporary high levels of oxygen in the tissue promote many positive health factors. High oxygen
directly destroys many microbes, stimulates immune cleanup and protective function and increases
energy production which hastens healing.
What is a Treatment Like?
A treatment begins as the pressure inside the hyperbaric chamber gradually increases. The pressure
change is felt mainly in the ears, similar to the fullness felt in the ears when landing in an airplane or
mountainous driving. During compression, the chamber may warm slightly for about ten minutes, then
cools to room temperature when reaching treatment pressure. During the treatment, patients may
watch a video, read, listen to music or sleep. Most treatments last about sixty minutes.
Ending a Treatment
While the chamber decompresses at the end of the treatment, the ears again experience a popping
sensation as they adjust to the pressure change. Some patients report feeling light headed for a few
minutes immediately following a treatment, but this is brief, and they are quickly able to continue with
their normal daily activities such as working or driving.
What is the History of HBOT?
Hyperbaric chambers have been in use for centuries, as early as 1662. Hyperbaric oxygen therapy has
been used clinically since the mid 1800's. HBOT was tested and developed by the U.S. Military after
World War I. It has been used safely since the 1930's to help treat deep sea divers with decompression
sickness. Clinical trials in the 1950's uncovered a number of benefits from exposure to hyperbaric
oxygen. These experiments were the forerunners of contemporary applications of HBOT in the clinical
Benefits of Hyperbaric Oxygen
Studies Reveal the Following Health Benefits of HBOT:
Speeds healing. 1
Increases energy. 1
Recover from sickness quicker. 2-6
Eliminate toxins quicker. 2
Helps rid exercise related soreness from muscles quicker. 3
Quick joint pain relief. 4-5
Studies show HBOT under pressure:
Has a drug-like effect prompting healing. 7,8,30,33,38
Improves infection fighting. 10,11,12,13,14,15
Has a direct affect on infections. 12,18,19
Reduces inflammation. 37
Reduces swelling. 34
Successfully delivers oxygen to areas of poor circulation. 17
Improves effectiveness of some antibiotics. 20,21,22,23,24,25,26
Simulates wound healing and tissue repair. 9,16,27,29,32,36,39
Promotes new skin growth. 28,31
Minimizes dangerous blood clotting conditions. 35
HBOT has positive effects on the great majority of the pathological processes promoting wound repair
and healing through a variety of mechanisms, many of which are mediated by signal induction
(drug-like) effects on DNA and nitric oxide.
1 - Uses of hyperbaric oxygen therapy., Kindwall EP., Department of Plastic and Reconstructive Surgery, Medical College
of Wisconsin, Milwaukee.
2 - Oxygen tensions and infections: modulation of microbial growth, activity of antimicrobial agents, and immunologic
responses., Park MK, Myers RA, Marzella L. , Clin Infect Dis. 1992 Mar;14(3):720-40., Department of Pathology, School
of Medicine, University of Maryland, Baltimore 21201.
3 - Hyperbaric oxygenation and blood lactate clearance: study in sixty male naval cadets. Sueblinvong T, Egtasaeng N,
Sanguangrangsirikul S., J Med Assoc Thai. 2004 Sep;87 Suppl 2:S218-22. Department of Biochemistry, Faculty of
Medicine, Chulalongkorn University, Bangkok 10330, Thailand.
4 - Effects of hyperbaric oxygen on inflammatory response to wound and trauma: possible mechanism of action. Al-Waili
NS, Butler GJ., ScientificWorldJournal. 2006 Apr 3;6:425-41.
5 - Uses of hyperbaric oxygen therapy., Kindwall EP., Department of Plastic and Reconstructive Surgery, Medical College
of Wisconsin, Milwaukee.
6 - Oxygen tensions and infections: modulation of microbial growth, activity of antimicrobial agents, and immunologic
responses. Park MK, Myers RA, Marzella L., Clin Infect Dis. 1992 Mar;14(3):720-40. Department of Pathology, School of
Medicine, University of Maryland, Baltimore 21201.
7 - Schaffer MR, Tantry U, van Wesep RA, Barbul A. Nitric oxide metabolism in wounds. J Surg Res 1997; 71:25-31.
8 - Boykin JV. The nitric oxide connection: hyperbaric oxygen therapy, becaplermin, and diabetic ulcer management.
Adv Skin Wound Care 2000; 13: 169-74.
9 - Niinikoski J. The effect of oxygen supply on wound healing and formation of experimental granulation tissue. Acta
Physiol Scand 1969; 334: 1-72.
10 - Knighton DR, Halliday B, Hunt TK. Oxygen as an antibiotic: The effect of inspired oxygen on infection. Arch Surg
1984; 119: 199-204.
11 - Knighton DR, Halliday B, Hunt TK. Oxygen as an antibiotic: A comparison of inspired oxygen concentration and
antibiotic administration on in vivo bacterial clearance. Arch Surg 1986; 121: 191-195.
12 - Mader JT, Brown GL, Guckian JC, et al. A mechanism for the amelioration by hyperbaric oxygen of experimental
staphylococcal osteomyelitis in rabbits. J Infect Dis 1980; 142: 915-922.
13 - Mader JT, Adams KR, Sulton TE. Infectious diseases: pathophysiology and mechanisms of hyperbaric oxygen. J
Hyperbaric Med 1987; 2: 133-140.
14 - Thom SR, Lauermann MW, Hart GB. Intermittent hyperbaric oxygen therapy for reduction of mortality in
experimental polymicrobial sepsis. J Infect Dis 1986; 154: 504-510.
15 - Thom SR. Hyperbaric oxygen therapy in septicemia. J Hyperbaric Med 1987; 2: 141-146.
16 - Siddiqui A, Davidson JD, Mustoe TA. Ischemic tissue oxygen capacitance after hyperbaric oxygen therapy: A new
physiologic concept. Plast Reconstr Surg 1997; 99: 148-155.
17 - Brummelkamp WH. Considerations on hyperbaric oxygen therapy at three atmospheres absolute for clostridial
infections type welchii. Ann NY Acad Sci 1965; 117: 688-699.
18 - McCord JM, Keele B, Fridovich I. An enzyme based theory of obligate anaerobiosis: the physiological function of
superoxide dismutase. Proc Natl Acad Sci USA 1971; 68: 1024-1027.
19 - McAllister TA, Stark JM, Norman JN, Ross RM. Inhibitory effects of hyperbaric oxygen on bacteria and fungi. Lancet
1963; 2: 1040-1042.
20 - Verklin RM, et al. Alteration of effectiveness of antibiotics by anaerobiosis. J Lab Clin Med 1977; 89(1): 65-71.
21 - Harrell LJ, et al. Effect of anaerobiosis on antimicrobial susceptibility of staphylococci. Antimicrob Agents Chemother
1977; 11: 1077-1078.
22 - Keck PE, Gottlieb SF, Conley J. Interaction of increased pressures of oxygen and sulfonamides on the in vitro and in
vivo growth of pathogenic bacteria. Undersea Biomed Res 1980; 7: 95-106.
23 - Norden CW. Experimental osteomyelitis V. Therapeutic trials with oxacillin and sisomicin alone and in combination. J
Infect Dis 1978; 137: 155-160.
24 - Tack KJ, et al. Increased minimum inhibitory concentrations with anaerobiasis for tobramycin, gentamicin, and
amikacin, compared to latamoxef, piperacillin, chloramphenicol, and clindamycin. Chemotherapy 1985; 33: 204-210.
25 - Adams KR, Mader JT. Aminoglycoside potentiation with adjunctive hyperbaric oxygen therapy in experimental
Pseudomonas aeruginosa osteomyelitis. Undersea Biomedical Research 1987; 14(2), Suppl: 37-8.
26 - Adams KR, Sutton TE, Mader JT. In vitro potentiation of tobramycin under hyperoxic conditions. Undersea
Biomedical Research 1987; 14(2), Suppl: 37.
27 - Winter GD, Perrins DJD. Effects of hyperbaric oxygen treatment on epidermal regeneration. In: Proceedings of the
Fourth International Congress on Hyperbaric Medicine. Wada J, Iwa T, eds. The Williams and Wilkins Co., Baltimore, MD,
28 - Ketchum SA III, Thomas AN, Hall AD. Angiographic studies of the effects of hyperbaric oxygen on burn wound
revascularization. In: Proceedings of the Fourth International Congress on Hyperbaric Medicine. Wada J, Iwa T, eds. The
Williams and Wilkins Co., Baltimore, MD, 1970, p.388-394.
29 - Zhao LL, Davidson JD, Wee SC, Roth SI, Mustoe TA. Effect of hyperbaric oxygen and growth factors on rabbit ear
ischemic ulcers. Arch Surg 1994; 129: 1043-1049.
30 - Wu L, Mustoe TA. Effect of ischemia on growth factor enhancement of incisional wound healing. Surgery 1995; 117:
31 - Sheikh AY, Gibson JJ, Rollins MD, et al. Effect of hyperoxia on vascular endothelial growth factor levels in a wound
model. Arch Surg 2000; 135: 1293-1297.
32 - Garret IR, et al. Oxygen-derived free radicals stimulate osteoclastic bone resorption in rodent bone in vitro and in
vivo. J Clin Invest 1990; 85(3): 632-639.
33 - Buras JA, Stahl GL, Svoboda KKH, Reenstra WR. Hyperbaric oxygen downregulates ICAM-1 expression induced by
hypoxia and hypoglycemia: the role of NOS. Am J Physiol Cell Physiol 2000; 278: C292-302.
34 - Bruch-Gerharz D, Ruzicka T, Kolb-Bachofen V. Nitric oxide in human skin: current status and future prospects. J
Invest Dermatol 1998; 110: 1-7.
35 - Beckman JS. The physiological and pathological chemistry of nitric oxide. In: Nitric Oxide. Lancaster J, ed. Academic
Press, New York, NY, 1996, p.1-71.
36 - Noiri E, Lee D, Testa J, et al. Podokinesis in endothelial cell migration: role of nitric oxide. Am J Physiol 1998; 274(1
Pt 1): C236-C244.
37 - Lefer AM, Lefer DJ. The role of nitric oxide and cell adhesion molecules on the microcirculation in
ischaemia-reperfusion. Cardiovasc Res 1996; 32: 743-51.
38 - Shen YH, Wang XL, Wilcken DE. Nitric oxide induces and inhibits apoptosis through different pathways. FEBS Lett
1998; 433(1-2): 125-31.
39 - Papapetropoulos A, Garcia-Cardena G, Madri JA, Sessa WC. Nitric oxide production contributes to the angiogenic
properties of vascular endothelial growth factor in human endothelial cells. J Clin Invest 1997; 100: 3131-9.